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Cervical Cancer

Case Story Video: Scoring of PD-L1 IHC 22C3 pharmDx in Cervical Cancer

    clockimg 16m
  • Case Walkthrough
  • Intermediate
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Professor Bharat Jasani reviews and explains PD-L1 scoring on two challenging cervical cancer cases. The professor introduces three useful techniques for determining CPS in near-cutoff cases: The Numerator Target Method, the Hotspot Method and the Rolling Method. He then proceeds to illustrate the usefulness of these methods in two cervical cancer cases. 

This case walkthrough focuses on two cervical cases that exhibit different staining characteristics. The presenter explains how the differences in staining characteristics lead to a different approach to scoring CPS in the two cases: 

  • The first case is assessed using the Hotspot Method. 
  • The second case is assessed using a combination of Hotspot Method and the Rolling Method.

Bharat Jasani, Prof.

Emeritus Professor in Cancer Pathology at Cardiff University, Director and Founder of B&A Pathology Consultancy Ltd

Related Training

This website addresses general principles for CDx scoring and is for education purposes only. Not all cancer indications mentioned are approved worldwide. Please refer to local Instructions for Use for further details.​ D0118721_1.00