CPS
  • Home

Sign in or register to track your progress, save, and view your completed history.

Esophageal Cancer

Case Story Video: Scoring of PD-L1 IHC 22C3 pharmDx in Esophageal Cancer

    clockimg 16m
  • Case Walkthrough
  • Intermediate
 saveimgSave unsaveimgUnsave

Professor Bharat Jasani reviews and explains PD-L1 scoring on two challenging esophageal cancer cases. The professor introduces three useful techniques for determining CPS in near-cutoff cases: The Numerator Target Method, the Hotspot Method and the Rolling Method. He then proceeds to illustrate the usefulness of these methods in two esophageal cancer cases. 

This case walkthrough focuses on two esophageal cases that exhibit different staining characteristics. The presenter explains how the differences in staining characteristics lead to choosing one scoring technique over another:

  • The first case is assessed using a combination of Hotspot Method and the Rolling Method.
  • The second case is assessed using the Hotspot Method.

Bharat Jasani, Prof.

Emeritus Professor in Cancer Pathology at Cardiff University, Director and Founder of B&A Pathology Consultancy Ltd

Related Training

This website addresses general principles for CDx scoring and is for education purposes only. Not all cancer indications mentioned are approved worldwide. Please refer to local Instructions for Use for further details.​​D0118723_1.00