Podcast Episode 4: Tissue Issues - Overcoming Sample Limitations for PD-L1 Testing

In this fourth episode of the “Dialogues in CDx” podcast series, we explore the issue of sample limitations and how pathologists can address them when performing PD-L1 testing. Two leaders in gastrointestinal pathology join the host Scott W. Boyer in an engaging discussion of the main challenges and solution strategies.

Dr. Mar Iglesias Coma is Head of the Pathology Department at Hospital del Mar in Barcelona and specializes in gastrointestinal pathology. Since 2008, Dr. Iglesias has served as an associate professor at the Faculty of Medicine in Pathology, and is a contributor to multiple innovation projects, particularly within the fields of digital pathology, tools for multidisciplinary tumor committees, biomarkers, and laboratory applications.

Also joining the conversation is Professor Manuel Rodriguez-Justo, a consultant in gastrointestinal pathology and haematopathology at University College London Hospitals as well as a Professor of Onco-Pathology at UCL-Cancer Institute. Professor Rodriguez-Justo has implemented molecular pathways and biomarker testing in gastrointestinal cancers and is involved in designing and developing multiple national and multicenter trials.

Topics you’ll hear about in this episode include:

• The role of preanalytical variables
• Overcoming tissue heterogeneity and ensuring sufficient sample for reflex testing
• The importance of concordance and multidisciplinary tumor boards
• The impact on patients

The views and opinions expressed by the guests on this podcast are their own and do not necessarily reflect the views or opinions of the host or of Agilent.
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