Esophageal Cancer, Head & Neck Cancer

Navigating CPS Denominator Challenges

Join Agilent CDx Pathologist, Dr. Kurt Mathews, as he walks through Head & Neck Squamous Cell Carcinoma (HNSCC) and Esophageal Squamous Cell Carcinoma (ESCC) cases stained with PD-L1 IHC 22C3 pharmDx. This video reviews approaches for determining the CPS denominator in cases with challenging or ambiguous morphology.​


The Spotlight Video Series walks you through Combined Positive Score (CPS)​ principles and scoring strategies for cases stained with PD-L1 IHC 22C3 pharmDx. Through this engaging series, Agilent PD-L1 experts will help you to confidently:​

  • Evaluate H&E, NCR, and PD-L1 slides for adequacy ​
  • Understand inclusion/exclusion criteria and other core principles of CPS
  • Determine the best approaches for scoring cases based on specific characteristics and features​
  • Navigate challenging morphology and staining characteristics​

 

Kurt Mathews, MD​

Pathologist​, Agilent Technologies


Related Training

This website addresses general principles for CDx scoring and is for education purposes only. Not all cancer indications mentioned are approved worldwide. Please refer to local Instructions for Use for further details.​D0114783_1.00